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Radiation Oncology

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The Beamline Bulletin

Expert Gallery Profiles

Submissions from 2020 2020

Tissue Oxygenation Changes in Response to Radiation Therapy in Breast Cancer Subjects Using Near-Infrared Optical Imaging, Corina Beiner, Maria-Amelia Rodrigues, and Michael Chuong

High-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539, Minesh Mehta

Putative Abscopal Effect in Three Patients Treated by Combined Radiotherapy and Modulated Electrohyperthermia, Minesh Mehta

Stereotactic Radiosurgery for Non-Functioning Pituitary Adenomas: Meta-Analysis and International Society of Stereotactic Radiosurgery (ISRS) Practice Opinion, Rupesh Kotecha and Muni Rubens

Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches, Rupesh Kotecha

Residual setup errors in cranial stereotactic radiosurgery without six degree of freedom robotic couch: Frameless versus rigid immobilization systems, Matthew Hall

Characterization of Positional Accuracy of a Double-Focused and Double-Stack Multileaf Collimator on an MR-Guided Radiotherapy (MRgRT) Linac using an IC-Profiler Array, Kathryn Mittauer

Minimal acute toxicity from proton beam therapy for major salivary gland cancer, Michael Chuong

Proton beam therapy for liver cancers, Michael Chuong

Quantification of radiation and imaging isocenter coincidence of a multi-room PBS proton therapy system, Suresh Rana, Jaafar Bennouna, and Alonso Gutierrez

Biological activity of weekly ONC201 in adult recurrent glioblastoma patients, Yazmin Odia and Minesh Mehta

Clinical experience of ONC201 in patients with recurrent H3 K27M-mutant spinal cord glioma, Yazmin Odia and Minesh Mehta

CTIM-22. PHASE 1 TRIAL OF OSIMERTINIB WITH STEREOTACTIC RADIOSURGERY (SRS) IN PATIENTS WITH BRAIN METASTASES FROM EGFR POSITIVE NON-SMALL-CELL LUNG CANCER (NSCLC), Rupesh Kotecha

CTNI-17. CLINICAL EFFICACY AND PREDICTIVE BIOMARKERS OF ONC201 IN H3 K27M-MUTANT DIFFUSE MIDLINE GLIOMA, Minesh Mehta, Yazmin Odia, Matthew Hall, and Doured Daghistani

Evaluation of spot size using volumetric repainting technique on a ProteusPLUS PBS Proton Therapy System, Suresh Rana, Jaafar Bennouna, and Alonso Gutierrez

Favorable Initial Outcomes of Abdominopelvic Reirradiation Using Dose-Escalated Magnetic Resonance Image-Guided Radiation Therapy, John Bryant, Kathryn Mittauer, Rupesh Kotecha, Jessika Contreras, Diane Alvarez, Noah Kalman, Matthew Hall, Gustavo Luciani, Tino Romaguera, Vivek Mishra, Minesh Mehta, Alonso Gutierrez, and Michael Chuong

HGG-18. CLINICAL EFFICACY OF ONC201 IN THALAMIC H3 K27M-MUTANT GLIOMA, Minesh Mehta, Yazmin Odia, Matthew Hall, and Doured Daghistani

Multi-institutional validation of brain metastasis velocity, a recently defined predictor of outcomes following stereotactic radiosurgery, Rupesh Kotecha

ONC201 in previously irradiated pediatric H3 K27M-mutant glioma or newly diagnosed DIPG, Yazmin Odia, Matthew Hall, and Doured Daghistani

Pulsed-reduced dose rate (PRDR) radiotherapy for recurrent primary central nervous system malignancies: dosimetric and clinical results, Tugce Kutuk, Alexander Mohler, Nicole McAllister, Matthew Hall, Martin Tom, Haley Appel, Ranjini Tolakanahalli, Alonso Gutierrez, Yazmin Odia, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha

The Utility of PET/Computed Tomography for Radiation Oncology Planning, Surveillance, and Prognosis Prediction of Gastrointestinal Tumors, Michael Chuong

Submissions from 2019 2019

EBV-positive primary CNS lymphoma restricted to the conus medullaris in an immunocompetent host, Matthew Hall, Lyle Feinstein, Sergio Gonzalez-Arias, and Yazmin Odia

Impact of Air Gap on Intensity-Modulated Proton Therapy Breast Plans, Suresh Rana and Jaafar Bennouna

The association between BMI and BSA–temozolomide-induced myelosuppression toxicities: a correlative analysis of NRG oncology RTOG 0525, Minesh Mehta

Characterization and longitudinal assessment of daily quality assurance for an MR-guided radiotherapy (MRgRT) linac, Kathryn Mittauer

STAT-ART: The Promise and Practice of a Rapid Palliative Single Session of MR-Guided Online Adaptive Radiotherapy (ART), Kathryn Mittauer

Lack of Efficacy of the Neutropenic Diet in Decreasing Infections among Cancer Patients: A Systematic Review, Muni Rubens, Anshul Saxena, Peter McGranaghan, Emir Veledar, Ana Viamonte Ros, and Rupesh Kotecha

Feasibility study of utilizing XRV-124 scintillation detector for quality assurance of spot profile in pencil beam scanning proton therapy, Suresh Rana

Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201, Matthew Hall, Yazmin Odia, and Minesh Mehta

Prediction of Anal Cancer Recurrence After Chemoradiotherapy Using Quantitative Image Features Extracted From Serial (18)F-FDG PET/CT, Michael Chuong

Barriers to Accrual and Enrollment in Brain Tumor Trials, Minesh Mehta

Letter: When Less is More: Dexamethasone Dosing for Brain Tumors, Minesh Mehta

Measurements of in-air spot size of pencil proton beam for various air gaps in conjunction with a range shifter on a ProteusPLUS PBS dedicated machine and comparison to the proton dose calculation algorithms, Suresh Rana

The Impact of Sequencing PD-1/PD-L1 Inhibitors and Stereotactic Radiosurgery for Patients with Brain Metastasis, Rupesh Kotecha

Comparison of Epidemiology and Outcomes in Neuro-Oncology Between the East and the West: Challenges and Opportunities, Minesh Mehta

Epidermal growth factor receptor (EGFR) amplification rates observed in screening patients for randomized trials in glioblastoma, Minesh Mehta

Radiobiological and dosimetric impact of RayStation pencil beam and Monte Carlo algorithms on intensity-modulated proton therapy breast cancer plans, Suresh Rana and Jaafar Bennouna

Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933, Minesh Mehta

The Complexity of Managing Large Brain Metastasis, Rupesh Kotecha and Minesh Mehta

Updates in the management of intradural spinal cord tumors: a radiation oncology focus, Rupesh Kotecha and Minesh Mehta

Defining an Intermediate-risk Group for Low-grade Glioma: A National Cancer Database Analysis, Minesh Mehta

Survival and prognostic factors in patients with gastrointestinal cancers and brain metastases: have we made progress?, Michael Chuong and Minesh Mehta

Ten-year outcomes of moderately hypofractionated (70 Gy in 28 fractions) intensity modulated radiotherapy for localized prostate cancer, Rupesh Kotecha

Consensus Report From the Miami Liver Proton Therapy Conference, Michael Chuong and Alonso Gutierrez

Stereotactic radiosurgery with concurrent HER2-directed therapy is associated with improved objective response for breast cancer brain metastasis, Rupesh Kotecha

NRG brain tumor specialists consensus guidelines for glioblastoma contouring, Minesh Mehta

First clinical experience with DRD2/3 antagonist ONC201 in H3 K27M-mutant pediatric diffuse intrinsic pontine glioma: a case report, Matthew Hall, Yazmin Odia, Doured Daghistani, and Minesh Mehta

Development and long-term stability of a comprehensive daily QA program for a modern pencil beam scanning (PBS) proton therapy delivery system, Suresh Rana, Jaafar Bennouna, and Alonso Gutierrez

Management of patients with brain metastases from non-small cell lung cancer and adverse prognostic features: multi-national radiation treatment recommendations are heterogeneous, Minesh Mehta

MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges, Minesh Mehta

Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases, Rupesh Kotecha

Estimating survival in patients with gastrointestinal cancers and brain metastases: An update of the graded prognostic assessment for gastrointestinal cancers (GI-GPA), Michael Chuong and Minesh Mehta

CMET-06. AN ANALYSIS OF RESPONSE ENDPOINTS FOR BRAIN METASTASIS PATIENTS TREATED WITH STEREOTACTIC RADIOSURGERY AND PD(L)-1 INHIBITORS, Rupesh Kotecha

Influence of Residual Disease Following Surgical Resection in Newly Diagnosed Glioblastoma on Clinical, Neurocognitive, and Patient Reported Outcomes, Minesh Mehta

Low-Grade Glioma Radiotherapy Treatment and Trials, Minesh Mehta

Preoperative Vs Postoperative Radiosurgery For Resected Brain Metastases: A Review, Minesh Mehta

Submissions from 2018 2018

The Case for Proton Beam Therapy, Michael Chuong

Postoperative Management of Resected Brain Metastases: When Can Radiotherapy Be Deferred?, Minesh Mehta and Rupesh Kotecha

Evaluation of Proton Therapy Accuracy Using a PMMA Phantom and PET Prediction Module, Wen Hsi

Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool, Minesh Mehta

Recent advances in managing brain metastasis, Rupesh Kotecha and Minesh Mehta

Dosimetric Impact of Large Displacement of the Metal Port of the Tissue Expander in Intensity Modulated Proton Therapy, Jen Yu, Jaafar Bennouna, and Minesh Mehta

Onco-metabolism: defining the prognostic significance of obesity and diabetes in women with brain metastases from breast cancer, Minesh Mehta

Prognostic models for patients with brain metastases after stereotactic radiosurgery with or without whole brain radiotherapy: a validation study, Minesh Mehta

Stereotactic Radiosurgery (SRS) with Immune Checkpoint Inhibitor Therapy (ICI) for Patients with Brain Metastasis (BM): The Impact of Timing and Sequencing, Rupesh Kotecha

Ten-Year Outcomes and Toxicity with Moderately Hypofractionated (70 Gy in 28 fractions) Intensity-Modulated Radiation Therapy for Localized Prostate Cancer, Rupesh Kotecha

Treatment recommendations for elderly patients with newly diagnosed glioblastoma lack worldwide consensus, Minesh Mehta

What is the evidence for the clinical value of SBRT in cancer of the cervix?, Minesh Mehta

Proton therapy patterns of care among pediatric and adult patients with CNS tumors, Rupesh Kotecha

Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial, Minesh Mehta

Correlation of radiation dose and activity with clinical outcomes in metastatic colorectal cancer after selective internal radiation therapy using yttrium-90 resin microspheres, Michael Chuong

Effect of Switching Systemic Treatment After Stereotactic Radiosurgery for Oligoprogressive, Metastatic Renal Cell Carcinoma, Rupesh Kotecha

Proton beam therapy for gastrointestinal cancers: past, present, and future, Matthew Hall and Michael Chuong

Consolidative Whole-Brain Radiation Therapy Versus Autologous Stem Cell Transplant for Primary Central Nervous System Lymphoma: A Large Dose of Perspective and Perhaps a Lower Dose of Radiation Are in Order, Minesh Mehta

Combining immunotherapy with radiation therapy in thoracic oncology, Michael Chuong

Omitting radiosurgery in melanoma brain metastases: a drastic and dangerous de-escalation, Minesh Mehta

Pencil beam scanning versus passively scattered proton therapy for unresectable pancreatic cancer, Michael Chuong, Man Yam, and Minesh Mehta

Effect of Targeted Therapies on Prognostic Factors, Patterns of Care, and Survival in Patients With Renal Cell Carcinoma and Brain Metastases, Minesh Mehta

Intermediate-risk meningioma: initial outcomes from NRG Oncology RTOG 0539, Minesh Mehta

Short delay in initiation of radiotherapy for patients with glioblastoma- effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database, Minesh Mehta

(OA13) Stereotactic Radiosurgery and Concurrent Targeted Therapy: Improving the Response Rate for Breast Cancer Brain Metastasis, Rupesh Kotecha

Prognostic and predictive factors in patients with brain metastases from solid tumors: A review of published nomograms, Minesh Mehta

An evaluation of the stability of image quality parameters of Elekta X-ray volume imager and iViewGT imaging systems, Alonso Gutierrez

Repeat reirradiation of the spinal cord: multi-national expert treatment recommendations, Minesh Mehta

A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: Results of NRG Oncology RTOG 0913, Minesh Mehta

Brain Metastases in Lung Cancer With Targetable Mutations-Reply, Minesh Mehta

Minimal toxicity after proton beam therapy for prostate and pelvic nodal irradiation: results from the proton collaborative group REG001-09 trial, Michael Chuong

Modeling the target dose fall-off in IMRT and VMAT planning techniques for cervical SBRT, Alonso Gutierrez

The Evolving Role of Tumor Treating Fields in Managing Glioblastoma: Guide for Oncologists, Minesh Mehta

Control versus cognition: the changing paradigm of adjuvant therapy for resected brain metastasis, Minesh Mehta

Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells, Minesh Mehta

Adaptive planning and toxicities of uniform scanning proton therapy for lung cancer patients, Suresh Rana

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group, Minesh Mehta

Dosimetric Evaluation of Pinnacle's Automated Treatment Planning Software to Manually Planned Treatments, Alonso Gutierrez

Early Objective Response as a Prognosticator for Final Objective Response and Survival following SRS for Brain Metastases Treated with Concurrent Systemic Therapy, Rupesh Kotecha

Improving the therapeutic index for nonoperable esophageal cancer patients with modern radiation technologies, Michael Chuong and Matthew Hall

Mid/Distal Esophageal Cancer and Gastroesophageal Junction Cancer (Siewert Type I and II), Michael Chuong

Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02, Minesh Mehta

Submissions from 2017 2017

Estimating Survival in Melanoma Patients With Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA), Minesh Mehta

Evidence-based Review on the Use of Proton Therapy in Lymphoma From the Particle Therapy Cooperative Group (PTCOG) Lymphoma Subcommittee, Michael Chuong