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Submissions from 2023

Dose-escalated proton therapy with concurrent and adjuvant immunotherapy for chordoma: Early results and toxicities from a single institution case series ​, Matthew Hall, Yazmin Odia, Minesh Mehta, Muni Rubens, Ranjini Tolakanahalli, Alonso Gutierrez, Keitrina Mair, Katherine Von Werne, and Carlos Rios

Dosimetric evaluation of prototype non-metallic breast expander for intensity modulated proton therapy ​, Kristen McConnell, Zachary Fellows, Joseph Panoff, Eduardo Pons, Alonso Gutierrez, Andrew Wroe, and Ryan Zielan

Estimating the risk of developing hypothyroidism in comprehensive breast cancer patients with sensitivity analysis computed from patient-setup and proton-range uncertainties, Andrew Wroe, Marcio Fagundes, Minesh Mehta, Alonso Gutierrez, and Jen Yu

Multi-institutional experience of proton therapy for osteosarcoma in the Proton Collaborative Group (PCG) prospective registry, Matthew Hall, Keitrina Mair, and Katherine Von Werne

Proton craniospinal irradiation for patients with solid tumor leptomeningeal metastasis: Initial real-world clinical experience, Tugce Kutuk, Haley Appel, Zachary Fellows, Alonso La Rosa de los Rios, Yazmin Odia, Matthew Hall, Manmeet Ahluwalia, Minesh Mehta, Rupesh Kotecha, and Sreenija Yarlagadda

Proton craniospinal irradiation for patients with solid tumor leptomeningeal metastasis: Suggested planning approaches for prior irradiation patients, Zachary Fellows, Andrew Wroe, Rupesh Kotecha, Matthew Hall, Minesh Mehta, and Alonso Gutierrez

The Initial Clinical Experience with an Interactive, Multi-Language, App-Based Neurocognitive Evaluation Program for Proton Therapy on CNS Malignancies, Tugce Kutuk, Rupesh Kotecha, Yazmin Odia, Matthew Hall, Haley Appel, Miguel Ramirez Menendez, Manmeet Ahluwalia, Minesh Mehta, and Alonso La Rosa de los Rios

A randomized phase 2 trial of encorafenib + binimetinib + nivolumab vs ipilimumab + nivolumab in BRAFV600-mutant melanoma brain metastases: SWOG S2000 (NCT# 04511013). 2023 American Society of Clinical Oncology, Rupesh Kotecha

Evaluating the diagnostic performance of 18F-fluciclovine for detection of recurrent brain metastases after radiation therapy: Results from a prospective phase 2 trial. 2023, Rupesh Kotecha

Evaluating the Diagnostic Performance of Leptomeningeal Diagnosis with CNSide™ Compared to Standard Cytology, Haley Appel, Anshul Saxena PhD, Rupesh Kotecha, Alexander Mohler, Matthew Hall, Manmeet Ahluwalia, Minesh Mehta, Yazmin Odia, and Serguei Castaneda

Prophylactic Cranial Irradiation in Small Cell Lung Cancer Patients in the Era of Magnetic Resonance Imaging: A Systematic Review and Meta-analysis, Manmeet Ahluwalia and Minesh Mehta

SM: RANO 2.0: Proposal for an Update to the Response Assessment in Neuro-Oncology (RANO) Criteria for High- and Low-Grade Gliomas in Adults, Minesh Mehta

Tumor Treating Fields (TTFields) therapy with standard of care (SOC) systemic therapy in advanced non-small cell lung cancer (aNSCLC) following platinum failure: Final results of the phase 3, randomized LUNAR study, Rupesh Kotecha

A machine learning based-personalized plan selection methodology for reducing skin toxicity in proton pencil beam scanning, Michael Kasper and Suresh Rana

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Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010-2019 Retrospective Cohort Study, Shreya Saxena, Atulya Khosla, Ahmad Ozair, Rupesh Kotecha, and Manmeet Ahluwalia

Feasibility study of utilizing Sphinx for quality assurance in uniform scanning proton therapy, Suresh Rana

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Temporally modulated pulsed proton re-irradiation (TMPPR) for recurrent high-grade gliomas, Alonso La Rosa de los Rios, Alonso Gutierrez, Yazmin Odia, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha

Dosimetric Comparison of GammaTile® Implants to Stereotactic Radiotherapy for Recurrent Brain Metastasis Resection Cavities., Robert Herrera, Rupesh Kotecha, D Jay Wieczorek, Zachary Fellows, Vibha Chaswal, Vivek Mishra, Michael McDermott, Vitaly Siomin, Minesh Mehta, Alonso Gutierrez, and Ranjini Tolakanahalli

GammaTile® brachytherapy versus stereotactic radiotherapy: A dosimetric comparison for the treatment of recurrent brain metastasis resection cavities, Robert Herrera, Rupesh Kotecha, Tugce Kutuk, D Jay Wieczorek, Zachary Fellows, Vibha Chaswal, Vivek Mishra, Michael McDermott, Minesh Mehta, Alonso Gutierrez, and Ranjini Tolakanahalli

Multi-institutional outcomes of proton beam therapy for hepatocellular carcinoma from the Proton Collaborative Group REG001-09 stud, Michael Chuong and Muni Rubens

The A3i System Significantly Reduces Treatment Times for MRLinac Radiotherapy, Robert Herrera, Michael Chuong, Kathryn Mittauer, James McCulloch, Diane Alvarez, Nema Bassiri-Gharb, Ranjini Tolakanahalli, Adeel Kaiser, Matthew Hall, Rupesh Kotecha, Minesh Mehta, and Alonso Gutierrez

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A Multi-Institutional Phase 2 Trial of Ablative 5-Fraction Stereotactic Magnetic Resonance-Guided On-Table Adaptive Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer, Kathryn Mittauer and Michael Chuong

A novel multi-task hybrid deep neural network (DNN) predicts tumor progression during MRgRT, Kathryn Mittauer and Rupesh Kotecha

Dosimetric evaluation of accelerated partial breast irradiation using SAVI & TRIUMPH-T trial regimen, Ranjini Tolakanahalli, Marc Morcos, Tino Romaguera, Alonso Gutierrez, Usha Abraham, Maria-Amelia Rodrigues, and Vibha Chaswal

Dosimetric Evaluation of an MR Linac System compared to Multiple Stereotactic Radiotherapy systems, Ranjini Tolakanahalli, Rupesh Kotecha, D Jay Wieczorek, Kathryn Mittauer, Nema Bassiri-Gharb, Matthew Hall, Michael Chuong, Minesh Mehta, Michael McDermott, and Alonso Gutierrez

Evaluation of an interactive, multi-language, neurocognitive app in CNS radiation oncology, Rupesh Kotecha, Tugce Kutuk, Muni Rubens, Yazmin Odia, Matthew Hall, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, Suyen Ramos, and Miguel Ramirez Menendez

Initial Assessment of Adaptive Pancreas SBRT Treatment Efficiency using ViewRay MRIdian A3i, Kathryn Mittauer, Robert Herrera, James McCulloch, Diane Alvarez, Ranjini Tolakanahalli, Adeel Kaiser, Matthew Hall, Rupesh Kotecha, Minesh Mehta, Michael Chuong, and Nema Bassiri-Gharb

Phase II trial of single-fraction SABR on 0.35T MRI-linac for thoracic, abdominal, and pelvic tumors, Michael Chuong, Kathryn Mittauer, Martin Tom, Noah Kalman, James McCulloch, Diane Alvarez, Paul Kaywin, Antonio Ucar, Federico Albrecht, Fernando De Zarraga, Santiago Aparo, Guilherme Rabinowits, Muni Rubens, Alonso Gutierrez, Rupesh Kotecha, and Carolina Rojas

Prognostic value of neutrophil/lymphocyte count in pancreas patients receiving ablative MR-guided RT, Michael Chuong, Robert Herrera, Muni Rubens, Antonio Ucar, Fernando De Zarraga, Santiago Aparo, Sarah Joseph, Matthew Hall, Rupesh Kotecha, Adeel Kaiser, and Gigi Estevez

Prospective Study Phase II Trial of Stereotactic MRI-Guided Adaptive Radiotherapy in 1 Fraction: Unplanned Interim Analysis, Michael Chuong, Kathryn Mittauer, Martin Tom, Noah Kalman, James McCulloch, Diane Alvarez, Paul Kaywin, Antonio Ucar, Federico Albrecht, Fernando De Zarraga, Santiago Aparo, Muni Rubens, Alonso Gutierrez, and Rupesh Kotecha

Quality of life after ablative 5-fraction radiation therapy from the phase II SMART pancreas trial, Michael Chuong and Kathryn Mittauer

Toxicity outcomes of dose-escalated MR-guided radiation therapy for abdominal and pelvic tumors, Tugce Kutuk, Michael Chuong, Kathryn Mittauer, Jessika Contreras, Adeel Kaiser, Matthew Hall, James McCulloch, Diane Alvarez, Minesh Mehta, Alonso Gutierrez, Rupesh Kotecha, Martin Tom, and Robert Herrera

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Rethinking classification and categorization of resection extent and its impact on patient survival in glioblastoma: Was Walter Dandy ahead of his time?, Rupesh Kotecha and Minesh Mehta

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ISRS Technical Guidelines for Stereotactic Radiosurgery: Treatment of Small Brain Metastases (≤1 cm in diameter), Rupesh Kotecha

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Neoadjuvant chemotherapy and stereotactic body radiation therapy for borderline resectable pancreas adenocarcinoma: influence of vascular margin status and type of chemotherapy, Michael Chuong

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The Rationale for Radiation Therapy in Alzheimer's Disease, Minesh Mehta

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Evaluating the intracranial activity of adagrasib, Rupesh Kotecha, Alonso La Rosa de los Rios, Tugce Kutuk, Manmeet Ahluwalia, and Minesh Mehta

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Post-mastectomy radiation therapy in HER-2 positive breast cancer after primary systemic therapy: Pooled analysis of TRYPHAENA and NeoSphere trials, Joseph Panoff and Youssef Zeidan

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Key Clinical Principles in the Management of Glioblastoma, Rupesh Kotecha, Yazmin Odia, Atulya Khosla, and Manmeet Ahluwalia

Phase I Dose Escalation Trial Combining Olaparib and Thoracic Radiation Therapy in Extensive-Stage Small Cell Lung Cancer, Rupesh Kotecha

Dosimetric Comparison of GammaTile Implants to Stereotactic Radiotherap, Robert Herrera, Rupesh Kotecha, Tugce Kutuk, D Jay Wieczorek, Vibha Chaswal, Michael McDermott, Vitaly Siomin, Minesh Mehta, Alonso Gutierrez, Ranjini Tolakanahalli, and Zachary Fellows

Dosimetric Evaluation of an MR Linac System Compared to Multiple Stereotactic Radiotherapy Delivery Systems for Large Brain Metastases, Ranjini Tolakanahalli, D Jay Wieczorek, Kathryn Mittauer, Matthew Hall, Minesh Mehta, Michael McDermott, Rupesh Kotecha, and Alonso Gutierrez

Implementation of an Interactive, Multi-Language, App-Based Neurocognitive Evaluation Program into Routine Stereotactic Radiosurgery Practice, Tugce Kutuk, Yazmin Odia, Matthew Hall, Haley Appel, Miguel Ramirez Menendez, Alexander Mohler, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha

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Variable Relative Biological Effectiveness of Proton Therapy Increases PET-Visible Mucosal Injury in Head and Neck Cancer Patients, Edgar Gelover Reyes, Raees Tonse, Surya Chundru, Adeel Kaiser, Len Coutinho, Ryan Zielan, Zachary Fellows, and Noah Kalman

Radiosurgery: What are the Questions we Should be Asking?, Minesh Mehta

Great Debates: Fractionated vs. Staged SRT for Brain Metastases, Minesh Mehta

Great Debates: Preopertavive vs. Postopertaive SRS for Brain Metastases, Minesh Mehta

Innovative Radiation Techniques, Minesh Mehta

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Hits and Misses in Novel Pancreatic and Rectal Cancer Treatment Options, Michael Chuong

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Modern Meningioma Methods: Molecular Diagnostics and High Dose Protons, Rupesh Kotecha and Minesh Mehta

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DNA Methylation and Histone Modification in Low-Grade Gliomas: Current Understanding and Potential Clinical Targets, Ahmad Ozair, Atulya Khosla, Rupesh Kotecha, Yazmin Odia, Michael McDermott, and Manmeet Ahluwalia

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Dosimetric delivery validation of dynamically collimated pencil beam scanning proton therapy, Jen Yu and Alonso Gutierrez

How Does the Updated WHO Classification System of Gliomas Impact our Recommendations for Radiation Dose and Technology in 2023?, Minesh Mehta

Keynote: Future of Proton Therapy, Minesh Mehta

An Update on NRG Trials of Hippocampal Avoidance, Minesh Mehta

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Implementation of superficial radiation therapy (SRT) using SRT-100 Vision™ for non-melanoma skin cancer in a Radiation Oncology clinic, Cecilia Lee, Stephan Davis, William Romaguera, Vibha Chaswal, Ranjini Tolakanahalli, Alonso Gutierrez, and Noah Kalman

Depatuxizumab-mafodotin in EGFR-amplified newly diagnosed glioblastoma: a phase III randomized clinical trial, Minesh Mehta

Proton Therapy for CNS and Leptomeningeal Indications, Minesh Mehta

Radiosurgery for Gliomas, Minesh Mehta

Radiosurgery in Clinical Practice, Minesh Mehta

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Racial disparities in clinical presentation, surgical procedures, and hospital outcomes among patients with hepatocellular carcinoma in the United States, Tugce Kutuk, Muni Rubens, Haley Appel, Michael Chuong, Adeel Kaiser, Matthew Hall, Jessika Contreras, Minesh Mehta, and Rupesh Kotecha

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OptImal Gamma kNife lIghTnIng sOlutioN (IGNITION) score to characterize the solution space of the Gamma Knife FIP optimizer for stereotactic radiosurgery, Ranjini Tolakanahalli, D Jay Wieczorek, Cecilia Lee, Martin Tom, Matthew Hall, Michael McDermott, Minesh Mehta, Rupesh Kotecha, and Alonso Gutierrez

Updates in CNS Malignancies, Minesh Mehta

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Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539, Minesh Mehta

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Accelerated hypofractionated magnetic resonance-guided adaptive radiotherapy for oligoprogressive non-small cell lung cancer, Alonso La Rosa de los Rios, Kathryn Mittauer, Michael Chuong, Matthew Hall, Tugce Kutuk, Nema Bassiri-Gharb, James McCulloch, Diane Alvarez, Raul Herrera, Alonso Gutierrez, Ranjini Tolakanahalli, Minesh Mehta, and Rupesh Kotecha

A study on inter-planner plan quality variability using a manual planning- or Lightning dose optimizer-approach for single brain lesions treated with the Gamma Knife(®) Icon™, Cecilia Lee, D Jay Wieczorek, Vibha Chaswal, Rupesh Kotecha, Matthew Hall, Minesh Mehta, Michael McDermott, Alonso Gutierrez, and Ranjini Tolakanahalli

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways, Minesh Mehta, Matthew Hall, Doured Daghistani, and Yazmin Odia

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Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010-2019 Retrospective Cohort Study, Shreya Saxena, Atulya Khosla, Ahmad Ozair, Rupesh Kotecha, and Manmeet Ahluwalia

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling, Minesh Mehta

Current drug development and trial designs in neuro-oncology: report from the first American Society of Clinical Oncology and Society for Neuro-Oncology Clinical Trials Conference, Minesh Mehta

Developing an AI-assisted planning pipeline for hippocampal avoidance whole brain radiotherapy, Minesh Mehta

Dosimetric Impact of Lesion Number, Size, and Volume on Mean Brain Dose with Stereotactic Radiosurgery for Multiple Brain Metastases, Alonso La Rosa De Los Rios, D Jay Wieczorek, Ranjini Tolakanahalli, Cecilia Lee, Tugce Kutuk, Matthew Hall, Michael McDermott, Minesh Mehta, Alonso Gutierrez, and Rupesh Kotecha

Editorial: Effects of radiation therapies on brain metastases, Rupesh Kotecha and Minesh Mehta

Low-Dose Whole Brain Radiation Therapy for Alzheimer's Dementia: Results From a Pilot Trial in Humans, Minesh Mehta

Management of Brain Metastases: A Review of Novel Therapies, Shreyas Bellur, Atulya Khosla, Rupesh Kotecha, Michael McDermott, and Manmeet Ahluwalia

Meta-Analysis of Rates and Risk Factors for Local Recurrence in Surgically Resected Patients With NSCLC and Differences Between Asian and Non-Asian Populations, Minesh Mehta

Multi-Institutional Outcomes of Patients Aged 75 years and Older With Pancreatic Ductal Adenocarcinoma Treated With 5-Fraction Ablative Stereotactic Magnetic Resonance Image-Guided Adaptive Radiation Therapy (A-SMART), Roberto Herrera, Muni Rubens, Adeel Kaiser, Antonio Ucar, Fernando De Zarraga, Santiago Aparo, Horacio Asbun, Ramon Jimenez, and Michael Chuong

National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities, Minesh Mehta, Manmeet Ahluwalia, and Rupesh Kotecha

NRG Oncology/RTOG1205: A Randomized Phase II Trial of Concurrent Bevacizumab and Reirradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma, Minesh Mehta

Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001, Minesh Mehta

Treatment of glioblastoma using MRIdian® A3i BrainTx™: Imaging and treatment workflow demonstration, Alonso La Rosa De Los Rios, Kathryn Mittauer, Amy Rzepczynski, Michael Chuong, Tugce Kutuk, Nicole McAllister, Matthew Hall, James McCulloch, Diane Alvarez, Roberto Herrera, Alonso Gutierrez, Ranjini Tolakanahalli, Yazmin Odia, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha

Tumor treating fields: narrative review of a promising treatment modality for cancer, Tugce Kutuk, Alonso La Rosa De Los Rios, Rupesh Kotecha, Minesh Mehta, and Michael Chuong

Submissions from 2022

Radiosurgery for Gliomas, Minesh Mehta

Radiosurgery in Clinical Practice, Minesh Mehta

Clinical outcomes comparing radiosurgery techniques for managing large brain metastases, Tugce Kutuk, Rupesh Kotecha, Ranjini Tolakanahalli, Haley Appel, D Jay Wieczorek, Michael McDermott, Manmeet Ahluwalia, Alonso Gutierrez, Minesh Mehta, and Martin Tom

Goldilocks and the Three Doses of Stereotactic Radiosurgery for Brain Metastases, Tugce Kutuk, Rupesh Kotecha, Ranjini Tolakanahalli, Haley Appel, Matthew Hall, D Jay Wieczorek, Michael McDermott, Manmeet Ahluwalia, Alonso Gutierrez, Minesh Mehta, and Martin Tom

NRG-BN010: A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on the Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma, Rupesh Kotecha and Minesh Mehta

Challenges in the Conduct of Proton vs. Photon Clinical Trials for Neurooncology, Advanced Clinical Trial Strategies: Therapeutic Development in NeuroOncology, Minesh Mehta

Role of Radiotherapy in Brain Metastases from Lung Cancer, Minesh Mehta

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Feasibility study of utilizing Sphinx Compact for quality assurance in uniform scanning proton therapy, Suresh Rana

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Association of Pretreatment Hippocampal Volume With Neurocognitive Function in Patients Treated With Hippocampal Avoidance Whole Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology/RTOG 0933, Minesh Mehta

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Deep Learning-Based Automatic Detection of Brain Metastases in Heterogenous Multi-Institutional MRI Sets: An Exploratory Analysis of NRG CC001, Minesh Mehta

An optimal solution study on the Leksell Gamma Knife® LightningTM optimizer for stereotactic radiosurgery of single brain metastasis, Rupesh Kotecha, D Jay Wieczorek, Martin Tom, Matthew Hall, Michael McDermott, Minesh Mehta, Alonso Gutierrez, and Ranjini Tolakanahalli

Dedicated Isotropic 3-D T1 SPACE Sequence Imaging for Radiosurgery Planning Improves Brain Metastases Detection and Reduces the Risk of Intracranial Relapse, Tugce Kutuk, Kevin Abrams, Martin Tom, Muni Rubens, Haley Appel, Matthew Hall, Ranjini Tolakanahalli, D Jay Wieczorek, Alonso Gutierrez, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha

Does Hippocampal Atrophy Correlate with Neurocognitive Outcomes One Year Following Radiotherapy? Results from a Prospective Trial, Matthew Hall, Katherine Von Werne, Muni Rubens, Rupesh Kotecha, Alexander Mohler, Yazmin Odia, Noah Kalman, Kevin Abrams, Andrew Wroe, Alonso Gutierrez, Michael Chuong, and Minesh Mehta

Evaluation of low dose rate intensity modulated proton therapy for re-irradiation of CNS malignancies, Andrew Wroe, Zachary Fellows, Tugce Kutuk, Minesh Mehta, Rupesh Kotecha, and Alonso Gutierrez

Feasibility and Initial Results of a Daily Wearable Patient-Tracking Device for Optimization of Radiation Machine Utilization and Timely Treatment Delivery, Adeel Kaiser, Lorrie Legrand, Maria Valladares, Michael Chuong, Rupesh Kotecha, Matthew Hall, Alonso Gutierrez, and Minesh Mehta

Impact of Treatment Modality on Post‐Radiation Imaging in Post‐Operative Head and Neck Cancers, Michael Chuong, Jessika Contreras, Matthew Hall, Alonso Gutierrez, Adeel Kaiser, Rupesh Kotecha, Andrew Wroe, and Noah Kalman

Longitudinal Assessment of Gross Tumor Volume in Abdominal and Pelvic Patients Undergoing MR-Guided Online Adaptive Radiotherapy as a Predictive Biomarker of Treatment Response, Kathryn Mittauer, Robert Herrera, Adeel Kaiser, Jessika Contreras, Matthew Hall, Noah Kalman, Tino Romaguera, James McCulloch, Diane Alvarez, Alonso Gutierrez, Minesh Mehta, Michael Chuong, and Rupesh Kotecha

Management of Cardiac Implantable Electronic Devices for Patients Receiving MR-Guided Radiotherapy: 4-Year Single Institution Experience, James McCulloch, Robert Herrera, Alonso Gutierrez, Tino Romaguera, Diane Alvarez, Rupesh Kotecha, Adeel Kaiser, Kevin Abrams, Minesh Mehta, Michael Chuong, and Kathryn Mittauer