See Also:
The Beamline Bulletin
Submissions from 2023
Phase II trial of single-fraction SABR on 0.35T MRI-linac for thoracic, abdominal, and pelvic tumors, Michael Chuong, Kathryn Mittauer, Martin Tom, Noah Kalman, James McCulloch, Diane Alvarez, Paul Kaywin, Antonio Ucar, Federico Albrecht, Fernando De Zarraga, Santiago Aparo, Guilherme Rabinowits, Muni Rubens, Alonso Gutierrez, Rupesh Kotecha, and Carolina Rojas
Prognostic value of neutrophil/lymphocyte count in pancreas patients receiving ablative MR-guided RT, Michael Chuong, Robert Herrera, Muni Rubens, Antonio Ucar, Fernando De Zarraga, Santiago Aparo, Sarah Joseph, Matthew Hall, Rupesh Kotecha, Adeel Kaiser, and Gigi Estevez
Prospective Study Phase II Trial of Stereotactic MRI-Guided Adaptive Radiotherapy in 1 Fraction: Unplanned Interim Analysis, Michael Chuong, Kathryn Mittauer, Martin Tom, Noah Kalman, James McCulloch, Diane Alvarez, Paul Kaywin, Antonio Ucar, Federico Albrecht, Fernando De Zarraga, Santiago Aparo, Muni Rubens, Alonso Gutierrez, and Rupesh Kotecha
Quality of life after ablative 5-fraction radiation therapy from the phase II SMART pancreas trial, Michael Chuong and Kathryn Mittauer
Toxicity outcomes of dose-escalated MR-guided radiation therapy for abdominal and pelvic tumors, Tugce Kutuk, Michael Chuong, Kathryn Mittauer, Jessika Contreras, Adeel Kaiser, Matthew Hall, James McCulloch, Diane Alvarez, Minesh Mehta, Alonso Gutierrez, Rupesh Kotecha, Martin Tom, and Robert Herrera
Rethinking classification and categorization of resection extent and its impact on patient survival in glioblastoma: Was Walter Dandy ahead of his time?, Rupesh Kotecha and Minesh Mehta
ISRS Technical Guidelines for Stereotactic Radiosurgery: Treatment of Small Brain Metastases (≤1 cm in diameter), Rupesh Kotecha
The Rationale for Radiation Therapy in Alzheimer's Disease, Minesh Mehta
Evaluating the intracranial activity of adagrasib, Rupesh Kotecha, Alonso La Rosa de los Rios, Tugce Kutuk, Manmeet Ahluwalia, and Minesh Mehta
Post-mastectomy radiation therapy in HER-2 positive breast cancer after primary systemic therapy: Pooled analysis of TRYPHAENA and NeoSphere trials, Joseph Panoff and Youssef Zeidan
Key Clinical Principles in the Management of Glioblastoma, Rupesh Kotecha, Yazmin Odia, Atulya Khosla, and Manmeet Ahluwalia
Phase I Dose Escalation Trial Combining Olaparib and Thoracic Radiation Therapy in Extensive-Stage Small Cell Lung Cancer, Rupesh Kotecha
Dosimetric Comparison of GammaTile Implants to Stereotactic Radiotherap, Robert Herrera, Rupesh Kotecha, Tugce Kutuk, D Jay Wieczorek, Vibha Chaswal, Michael McDermott, Vitaly Siomin, Minesh Mehta, Alonso Gutierrez, Ranjini Tolakanahalli, and Zachary Fellows
Dosimetric Evaluation of an MR Linac System Compared to Multiple Stereotactic Radiotherapy Delivery Systems for Large Brain Metastases, Ranjini Tolakanahalli, D Jay Wieczorek, Kathryn Mittauer, Matthew Hall, Minesh Mehta, Michael McDermott, Rupesh Kotecha, and Alonso Gutierrez
Implementation of an Interactive, Multi-Language, App-Based Neurocognitive Evaluation Program into Routine Stereotactic Radiosurgery Practice, Tugce Kutuk, Yazmin Odia, Matthew Hall, Haley Appel, Miguel Ramirez Menendez, Alexander Mohler, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha
Variable Relative Biological Effectiveness of Proton Therapy Increases PET-Visible Mucosal Injury in Head and Neck Cancer Patients, Edgar Gelover Reyes, Raees Tonse, Surya Chundru, Adeel Kaiser, Len Coutinho, Ryan Zielan, Zachary Fellows, and Noah Kalman
Radiosurgery: What are the Questions we Should be Asking?, Minesh Mehta
Great Debates: Fractionated vs. Staged SRT for Brain Metastases, Minesh Mehta
Great Debates: Preopertavive vs. Postopertaive SRS for Brain Metastases, Minesh Mehta
Innovative Radiation Techniques, Minesh Mehta
Hits and Misses in Novel Pancreatic and Rectal Cancer Treatment Options, Michael Chuong
Modern Meningioma Methods: Molecular Diagnostics and High Dose Protons, Rupesh Kotecha and Minesh Mehta
DNA Methylation and Histone Modification in Low-Grade Gliomas: Current Understanding and Potential Clinical Targets, Ahmad Ozair, Atulya Khosla, Rupesh Kotecha, Yazmin Odia, Michael McDermott, and Manmeet Ahluwalia
Dosimetric delivery validation of dynamically collimated pencil beam scanning proton therapy, Jen Yu and Alonso Gutierrez
Keynote: Future of Proton Therapy, Minesh Mehta
An Update on NRG Trials of Hippocampal Avoidance, Minesh Mehta
Implementation of superficial radiation therapy (SRT) using SRT-100 Vision™ for non-melanoma skin cancer in a Radiation Oncology clinic, Cecilia Lee, Stephan Davis, William Romaguera, Vibha Chaswal, Ranjini Tolakanahalli, Alonso Gutierrez, and Noah Kalman
Depatuxizumab-mafodotin in EGFR-amplified newly diagnosed glioblastoma: a phase III randomized clinical trial, Minesh Mehta
Proton Therapy for CNS and Leptomeningeal Indications, Minesh Mehta
Radiosurgery for Gliomas, Minesh Mehta
Radiosurgery in Clinical Practice, Minesh Mehta
OptImal Gamma kNife lIghTnIng sOlutioN (IGNITION) score to characterize the solution space of the Gamma Knife FIP optimizer for stereotactic radiosurgery, Ranjini Tolakanahalli, D Jay Wieczorek, Cecilia Lee, Martin Tom, Matthew Hall, Michael McDermott, Minesh Mehta, Rupesh Kotecha, and Alonso Gutierrez
Updates in CNS Malignancies, Minesh Mehta
Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539, Minesh Mehta
Accelerated hypofractionated magnetic resonance-guided adaptive radiotherapy for oligoprogressive non-small cell lung cancer, Alonso La Rosa de los Rios, Kathryn Mittauer, Michael Chuong, Matthew Hall, Tugce Kutuk, Nema Bassiri-Gharb, James McCulloch, Diane Alvarez, Raul Herrera, Alonso Gutierrez, Ranjini Tolakanahalli, Minesh Mehta, and Rupesh Kotecha
A study on inter-planner plan quality variability using a manual planning- or Lightning dose optimizer-approach for single brain lesions treated with the Gamma Knife(®) Icon™, Cecilia Lee, D Jay Wieczorek, Vibha Chaswal, Rupesh Kotecha, Matthew Hall, Minesh Mehta, Michael McDermott, Alonso Gutierrez, and Ranjini Tolakanahalli
Causes of Death Among Patients With Initially Inoperable Pancreas Cancer After Induction Chemotherapy and Ablative 5-fraction Stereotactic Magnetic Resonance Image Guided Adaptive Radiation Therapy, Michael Chuong, Roberto Herrera, Antonio Ucar, Santiago Aparo, Fernando De Zarraga, Domenech Asbun, Javier Jimenez, Horacio Asbun, Govindarajan Narayanan, Sarah Joseph, Rupesh Kotecha, Matthew Hall, Kathryn Mittauer, Diane Alvarez, James McCulloch, Tino Romaguera, Alonso Gutierrez, and Adeel Kaiser
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways, Minesh Mehta, Matthew Hall, Doured Daghistani, and Yazmin Odia
Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010-2019 Retrospective Cohort Study, Shreya Saxena, Atulya Khosla, Ahmad Ozair, Rupesh Kotecha, and Manmeet Ahluwalia
Correcting the drug development paradigm for glioblastoma requires serial tissue sampling, Minesh Mehta
Developing an AI-assisted planning pipeline for hippocampal avoidance whole brain radiotherapy, Minesh Mehta
Dosimetric Impact of Lesion Number, Size, and Volume on Mean Brain Dose with Stereotactic Radiosurgery for Multiple Brain Metastases, Alonso La Rosa De Los Rios, D Jay Wieczorek, Ranjini Tolakanahalli, Cecilia Lee, Tugce Kutuk, Matthew Hall, Michael McDermott, Minesh Mehta, Alonso Gutierrez, and Rupesh Kotecha
Editorial: Effects of radiation therapies on brain metastases, Rupesh Kotecha and Minesh Mehta
Low-Dose Whole Brain Radiation Therapy for Alzheimer's Dementia: Results From a Pilot Trial in Humans, Minesh Mehta
Management of Brain Metastases: A Review of Novel Therapies, Shreyas Bellur, Atulya Khosla, Rupesh Kotecha, Michael McDermott, and Manmeet Ahluwalia
Multi-Institutional Outcomes of Patients Aged 75 years and Older With Pancreatic Ductal Adenocarcinoma Treated With 5-Fraction Ablative Stereotactic Magnetic Resonance Image-Guided Adaptive Radiation Therapy (A-SMART), Roberto Herrera, Muni Rubens, Adeel Kaiser, Antonio Ucar, Fernando De Zarraga, Santiago Aparo, Horacio Asbun, Ramon Jimenez, and Michael Chuong
National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities, Minesh Mehta, Manmeet Ahluwalia, and Rupesh Kotecha
Racial disparities in clinical presentation, surgical procedures, and hospital outcomes among patients with hepatocellular carcinoma in the United States, Tugce Kutuk, Muni Rubens, Haley Appel, Michael Chuong, Adeel Kaiser, Matthew Hall, Jessika Contreras, Minesh Mehta, and Rupesh Kotecha
Treatment of glioblastoma using MRIdian® A3i BrainTx™: Imaging and treatment workflow demonstration, Alonso La Rosa De Los Rios, Kathryn Mittauer, Amy Rzepczynski, Michael Chuong, Tugce Kutuk, Nicole McAllister, Matthew Hall, James McCulloch, Diane Alvarez, Roberto Herrera, Alonso Gutierrez, Ranjini Tolakanahalli, Yazmin Odia, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha
Tumor treating fields: narrative review of a promising treatment modality for cancer, Tugce Kutuk, Alonso La Rosa De Los Rios, Rupesh Kotecha, Minesh Mehta, and Michael Chuong
Submissions from 2022
Radiosurgery for Gliomas, Minesh Mehta
Radiosurgery in Clinical Practice, Minesh Mehta
Clinical outcomes comparing radiosurgery techniques for managing large brain metastases, Tugce Kutuk, Rupesh Kotecha, Ranjini Tolakanahalli, Haley Appel, D Jay Wieczorek, Michael McDermott, Manmeet Ahluwalia, Alonso Gutierrez, Minesh Mehta, and Martin Tom
Goldilocks and the Three Doses of Stereotactic Radiosurgery for Brain Metastases, Tugce Kutuk, Rupesh Kotecha, Ranjini Tolakanahalli, Haley Appel, Matthew Hall, D Jay Wieczorek, Michael McDermott, Manmeet Ahluwalia, Alonso Gutierrez, Minesh Mehta, and Martin Tom
NRG-BN010: A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on the Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma, Rupesh Kotecha and Minesh Mehta
Role of Radiotherapy in Brain Metastases from Lung Cancer, Minesh Mehta
Feasibility study of utilizing Sphinx Compact for quality assurance in uniform scanning proton therapy, Suresh Rana
An optimal solution study on the Leksell Gamma Knife® LightningTM optimizer for stereotactic radiosurgery of single brain metastasis, Rupesh Kotecha, D Jay Wieczorek, Martin Tom, Matthew Hall, Michael McDermott, Minesh Mehta, Alonso Gutierrez, and Ranjini Tolakanahalli
Dedicated Isotropic 3-D T1 SPACE Sequence Imaging for Radiosurgery Planning Improves Brain Metastases Detection and Reduces the Risk of Intracranial Relapse, Tugce Kutuk, Kevin Abrams, Martin Tom, Muni Rubens, Haley Appel, Matthew Hall, Ranjini Tolakanahalli, D Jay Wieczorek, Alonso Gutierrez, Michael McDermott, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha
Does Hippocampal Atrophy Correlate with Neurocognitive Outcomes One Year Following Radiotherapy? Results from a Prospective Trial, Matthew Hall, Katherine Von Werne, Muni Rubens, Rupesh Kotecha, Alexander Mohler, Yazmin Odia, Noah Kalman, Kevin Abrams, Andrew Wroe, Alonso Gutierrez, Michael Chuong, and Minesh Mehta
Evaluation of low dose rate intensity modulated proton therapy for re-irradiation of CNS malignancies, Andrew Wroe, Zachary Fellows, Tugce Kutuk, Minesh Mehta, Rupesh Kotecha, and Alonso Gutierrez
Feasibility and Initial Results of a Daily Wearable Patient-Tracking Device for Optimization of Radiation Machine Utilization and Timely Treatment Delivery, Adeel Kaiser, Lorrie Legrand, Maria Valladares, Michael Chuong, Rupesh Kotecha, Matthew Hall, Alonso Gutierrez, and Minesh Mehta
Impact of Treatment Modality on Post‐Radiation Imaging in Post‐Operative Head and Neck Cancers, Michael Chuong, Jessika Contreras, Matthew Hall, Alonso Gutierrez, Adeel Kaiser, Rupesh Kotecha, Andrew Wroe, and Noah Kalman
Longitudinal Assessment of Gross Tumor Volume in Abdominal and Pelvic Patients Undergoing MR-Guided Online Adaptive Radiotherapy as a Predictive Biomarker of Treatment Response, Kathryn Mittauer, Robert Herrera, Adeel Kaiser, Jessika Contreras, Matthew Hall, Noah Kalman, Tino Romaguera, James McCulloch, Diane Alvarez, Alonso Gutierrez, Minesh Mehta, Michael Chuong, and Rupesh Kotecha
Management of Cardiac Implantable Electronic Devices for Patients Receiving MR-Guided Radiotherapy: 4-Year Single Institution Experience, James McCulloch, Robert Herrera, Alonso Gutierrez, Tino Romaguera, Diane Alvarez, Rupesh Kotecha, Adeel Kaiser, Kevin Abrams, Minesh Mehta, Michael Chuong, and Kathryn Mittauer
Master Class: Role Playing Exercise as an Educational Tool for Professional Career Preparation, Minesh Mehta
Multi-Institutional Experience of MR-guided Stereotactic Body Radiation Therapy for Adrenal Gland Metastases, Rupesh Kotecha, Robert Herrera, Tugce Kutuk, and Michael Chuong
Prophylactic Radiation Therapy versus Standard of Care for Patients with High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Trial, Rupesh Kotecha and Zhenwei Zhang
Pulsed reduced dose rate (PRDR) intensity-modulated radiotherapy for recurrent primary central nervous system malignancies: dosimetric and clinical results, Tugce Kutuk, Nicole McAllister, Matthew Hall, Martin Tom, Haley Appel, Ranjini Tolakanahalli, Alonso Gutierrez, Yazmin Odia, Alexander Mohler, Manmeet Ahluwalia, Minesh Mehta, and Rupesh Kotecha
Quantifying Success of a Daily Multidisciplinary Huddle in Radiation Oncology, Lorrie LeGrand, Tugce Kutuk, Maria Valladares, Muni Rubens, Monique Chisem, Gabriela Quintana, Haley Appel, Michael Chuong, Matthew Hall, Jessika Contreras, Marcio Fagundes, Alonso Gutierrez, Minesh Mehta, and Rupesh Kotecha
The Impact of Smaller Thyroid Gland Volume on the Risk of Developing Post-RT Hypothyroidism in Breast Cancer Patients Requiring Comprehensive Nodal Irradiation, Rupesh Kotecha, Tugce Kutuk, Andrew Wroe, Alonso Gutierrez, Minesh Mehta, and Marcio Fagundes
Stereotactic Radiosurgery in Clinical Practice: What are the Questions We Should be Asking?, Minesh Mehta
Interesting Case Presentation: Giant Sacral Chordomas, Minesh Mehta
Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions, Manmeet Ahluwalia and Minesh Mehta
Update on the Management of Brain Metastasis, Karanvir Singh, Shreya Saxena, Atulya Khosla, Michael McDermott, Rupesh Kotecha, and Manmeet Ahluwalia
Shaping the Landscape of Brain Metastases Research, Minesh Mehta
Shaping the Landscape of Brain Metastases Research: What Matters Most to Patients, Minesh Mehta
Providing Patients’ Tomorrow’s Care Today: Rapidly Bringing Discovery to the Bedside, Minesh Mehta
Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy, Yazmin Odia, Doured Daghistani, Zuanel Diaz, and Matthew Hall
Clinical Trials Lessons Learned, Minesh Mehta
From Bench to Bedside to Beam: Radiotherapy Advances for Brain Tumors., Minesh Mehta
Effect of frailty on hospital outcomes among patients with cancer in the United States: Results from the National Inpatient Sample, Muni Rubens, Adrian Cristian, Venkataraghavan Ramamoorthy, Anshul Saxena, Peter McGranaghan, Raees Tonse, and Emir Veledar
The Graded Prognostic Assessment (GPA) for Lung Cancer Patients with Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA including the Effect of Programmed Death Ligand-1 (PD-L1) and Other Prognostic Factors, Tugce Kutuk, Rupesh Kotecha, Manmeet Ahluwalia, and Minesh Mehta
Multimodality Approaches to Primary and Secondary Brain Tumors, Minesh Mehta
Radiation therapy alone versus radiation therapy plus radiofrequency ablation/vertebral augmentation for spine metastasis: trial in progress, Rupesh Kotecha, Brian Schiro, Justin Sporrer, Muni Rubens, Haley Appel, Martin Tom, and Minesh Mehta
Pearls and Pitfalls in Conducting Neuro-Oncology Trials: Reflections of Experienced Clinical Trialists, Minesh Mehta